Commercial drain cleaning involves utilizing various effective methods to address different types of blockages and build-up. Some commonly used methods include hydro-jetting, snaking, and chemical treatments. Hydro-jetting employs high-pressure water to forcefully clear out debris and build-up from the pipes, while snaking involves utilizing a drill to remove blockages physically. Chemical treatments can also be employed to dissolve organic matter and grease that may be causing the obstruction.