Commercial drain cleaning involves utilizing various effective methods to address different types of blockages and build-up. Some commonly used methods include hydro-jetting, snaking, and chemical treatments. Hydro-jetting employs high-pressure water to forcefully clear out debris and build-up from the pipes, while snaking involves utilizing an auger to remove blockages physically. Chemical treatments can also be employed to dissolve organic matter and grease that may be causing the obstruction.